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Some of the animals received lower doses, while others were given more. The dosage is said to have been "the allometrically scaled mouse equivalent doses of the maximum recommended human maintenance dose of CBD in EPIDIOLEX (20 mg/kg)." The research on mice we have referred to in this article shows that CBD is likely to affect the liver. We also know that CBD reduces the liver’s efficiency in metabolizing medicine by inhibiting the CYP450 enzymes.